Sage Test Technology

Why is the Sage ELISA test better than IgG4 ELISA or IgE tests?

While the IgE remains the standard for inhalant allergies, it fails miserably when diagnosing food related to chronic diseases. Most often a good history is better than an IgE test for foods. IgG4 is a protective antibody and is not clinically relevant. Sage ELISA tests for total IgG plus immune complexes, which then start the complement cascade.

Sage is far more comprehensive test for delayed food reactions. This does not mean that IgE or IgG4 tests are bad, they are just limited in the number of pathways of immunological responses. When delayed food reactions are missed by other methods, the patient's chronic conditions will not improve. The Sage ELISA Test is the preferred alternative to the direct method of measuring concentrations of allergen-specific immunoglobulins (i.e. RAST), which measures only single parameter mechanisms.

Sage Test Technology - Supporting Research Sage Test Technology - Supporting Research